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The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling formu,ation.

National Center for Biotechnology InformationU. Commercially available CHL topical powder was used for comparison. Please review our privacy policy. Medical Applications of Controlled Release. Received Dec 31; Accepted May Blackwell Scientific Publications; As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.

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Optimization of chlorphenesin emulgel formulation

They also exhibited higher drug release and antifungal activity than the CHL powder. This article has been cited by other articles in PMC.

The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. Transdermal controlled release systems. Marcel Dekker Inc; The Theory and Practice of Industrial Pharmacy. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon fofmulation for 3 months. Swarbrick J, Boylan JC, editors.

All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. Published online Sep 1.

Az J Pharm Sci. Formulation and evaluation of topical preparations containing phenol and local vesicants. Formulation and stability of chloramphenicol gel and emulgel. Analysis of data on the medicament release from ointments.

Bioavailability of salbutamol sulphate from different suppository formulations. Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.

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Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: A study of shear and compression deformations on hydrophilic gels of tretinoin.

Lea and Febiger; Egypt J Meulgel Sci. Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. Encyclopedia of Pharmaceutical Technology.

The Pharmaceutical Press; The drug release from all the emulgels was found to follow diffusion-controlled mechanism. Support Center Support Center.

Optimization of chlorphenesin emulgel formulation

The Complete Fomulation Reference. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design. Author information Article notes Copyright and License information Disclaimer.