Anthocleista is a genus of tree- and shrub-like tropical plants in the gentian family , tribe procera · Anthocleista rhizophoroides · Anthocleista scandens · Anthocleista schweinfurthii · Anthocleista vogelii · Anthocleista zambesiaca. Reference Sources. Entry From. Burkill, H.M. The useful plants of west tropical Africa, Vol 3. Names. Anthocleista vogelii Planch. [family LOGANIACEAE] . The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at.
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Animals models for studying diabetes mellitus. After two weeks, the levels of serum cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, alanine aminotransferase, aspartate amino transferase and creatinine of all the groups were analyzed.
Preparation of extract for administration: These constituents have been found in other natural products which exhibited antimalarial activity [ 36 ]. Hence, this study evaluates the anti-diabetic effect of the ethanolic root extract of Anthocleista vogelii in alloxan-induced diabetic rats.
Thirty-six mice were divided into six groups of six mice each. There are 66 citation in scholarly articles related to Anthocleista vogelii Planch. Precise statistics are unknown about increasing prevalence of malaria because many cases occur in rural areas where people do not have access to hospitals or the means to afford health care; hence, majority of cases are undocumented [ 5 ].
Acute toxicity studies Median lethal dose [LD 50 ] determination: The weight of food and volume of water consumed by rats in each group were measured daily as the difference between the quantity of food and water supplied and the amount remaining after 24 h, respectively.
Anthocleista vogelii Planch.
In Nigeria stems are hollowed out to make quivers. Several Anthocleista species are used for similar medicinal purposes and may be used as substitutes for each other.
These phytochemical compounds were also reported in another species, A. Anthocleista vogelii occurs in moist localities, in swamps, in Raphia groves, on river banks, in primary rainforest or secondary forest, from sea-level up to m altitude. In view of the recorded medicinal uses, more research into the chemical composition and pharmacological activities of Anthocleista vogelii is warranted. Blood was collected from the sacrificed mice by cardiac puncture using sterile syringes and needles.
Diabetes mellitus is a metabolic disorder, characterized by high fasting blood glucose level hyperglyceamia due to lack or insufficiency of insulin production by the beta cells of the islet of langerhans found in the pancreas or because the cells in the body are not sensitive to the insulin that is being produced by the beta cells Murray et al. Anthocleista vogelii ethanolic root extract elicited a significant decrease in body weight in alloxan-induced diabetic treated rats.
It showed that the stem bark of A.
Citation in scholarly articles. In Ghana a root decoction of Anthocleista vogelii and Combretum mucronatum Schumach. Enzymatic colorimetric end point method with cholesterol oxidase-peroxidase.
Email this to a friend Print Share on facebook Tweet this. The result of serum liver and kidney enzymes suggests that the extracts have the potential of reducing the serum levels of these enzymes in diabetic conditions.
View at Google Scholar M. Plant collection and extraction: In Ghana potash of the wood is used in making soap. Percentage parasitaemia and average percentage parasitaemia were calculated according to the following formula adopted by [ 28 ]: The authors declare that there is no conflict of interests regarding the publication of this paper.
Results of the preliminary phytochemical test carried out vogeloi the ethanolic stem bark extract of A.
Anthocleista vogelii Images
Food and water intake: Phytochemical analysis of the ethanolic stem bark extract of A. The stem bark decoctions are used traditionally in the treatment of malaria [ 19 ], as an antihelminthic especially for roundworms [ 20 ], as antidiarrhoea [ 21 ], and for treatment of epilepsy [ 22 ]. Tests with aqueous, hexane, acetone and methanol extracts of the stem bark in rats showed potent anti-ulcer properties, which could explain the traditional use in the treatment of stomach-ache.
Similar result was recorded using the methanolic stem bark extract of another species of the plant, A. The latter compound showed antimalarial activity in vivo vvogelii Plasmodium berghei. The animals were examined at 10, 30, 60 and min and at 4, 6 and 24 h for gross behaviourial changes as under phase 1 and subsequently for mortality.
Ghosh, Foundamentals of Experimental Pharmacologypp.
Glibenclamide belongs to the class of sulphonylureas anti-diabetic drug and anhtocleista has been widely accepted as a standard drug in diabetic animal experiments associated with mild or moderate hyperglycaemia Owolabi et al. Harborne, Phytochemical Methodspp. The study was conducted in the animal house and in the Department of Biochemistry, University of Uyo, Uyo.
Group G was infected with the parasite but was not treated with any extract.
The acute toxicity result shows that A.